For OS X the guide describes disabling USB and Firewire storage:
1. Log on with an administrator account.
2. Browse to ‘/System/Library/Extensions’ folder on the system disk.
3. Trash both IOUSBMassStorageClass.kext and IOFireWireSerialBusProtocolTransport.kext which are found in this directory.
4. Empty the trash.
5. Reboot the machine.
Disabling USB storage on a Windows platform is only a little more complicated: